Genetic mosaicism in epilepsy and neurodevelopmental disorders

Focal epilepsies and cortical malformations of development

Molecular and cellular mechanisms of epilepsy associated with somatic mutations

Main technique

Genetic and genomic analyses and single-cell OMICS of postoperative brain tissues

In vitro models (cortical organoids) & In vivo models (experimental mouse models)

Multidisciplinary approaches combining molecular biology, neurodevelopment, and pathophysiology

Address :
Hôpital Pitié-Salpêtrière 47 bd de l’Hôpital 75013 Paris

Team leader :
BAULAC Stephanie
Name of co-team leader :

Administrative Contact Name :


Website : Cliquez ici
Key words : #Mosaïcisme génétique et neurodeveloppement #Épilepsie focale et malformations corticales #Mutations somatiques# Organoïdes corticaux# Modèles murins #Thérapies de précision #Genetic mosaicism in neurodevelopment# Focal epilepsy# cortical malformations# Brain Somatic mutations# Brain organoids# Mouse models# Precision therapies