The 5 main objectives are:

To study the interactions between cholesterol and APP peptide to modulate the production of amyloid aggregates.

Characterize subcellular compartments where protein production is initiated.

To study the role of the cerebral lymphatic system in the drainage of pathological proteins.

To determine if specific proteins can be observed in patients with a different clinical profile.

To study the mechanisms involved in the specific targeting of certain brain structures.